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Melatonin Receptor 1B (MTNR1B) Goat Polyclonal Antibody

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SKU
AP31974PU-N
Melatonin Receptor 1B (MTNR1B) goat polyclonal antibody, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
5 Days*
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View other "MTNR1B or NP_005950.1" antibodies

Specifications
Specifications
Product Data
Application ELISA, IHC
Recommended Dilution

Peptide ELISA: 1/32000 (Detection limit).
Western blot: Preliminary experiments gave approx .48kDa and 37kDa bands in Human Brain (Cerebellum) lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 40.2kDa according to NP_005950.1. The 48kDa and 37kDa bands were successfully blocked by incubation with the immunizing peptide.
We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Immunohistochemistry on Paraffin Sections: 3-6 μg/ml. In paraffin embedded Cerebellum shows membranous staining primarily in Purkinje cells.
Reactivity Human
Antibody Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide with sequence from the C Terminus of Human MTNR1B (NP_005950.1).
Specificity This antibody detects MTNR1B at C-term
Buffer Tris saline, pH~7.3
State: Aff - Purified
State: Liquid purified Ig fraction
Stabilizer: 0.5% BSA
Preservative: 0.02% Sodium Azide
Concentration lot specific
Purification Immunoaffinity Chromatography
Conjugation Unconjugated
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name melatonin receptor 1B
Database Link
Background MTNR1b is a Melatonin Receptor that mediates the effects of melatonin in the retina and the photoperiodic control of neuroendocrine functions. It may also be involved in melatonin-induced immune enhancement.MTNR1b has been reported in adipose, brain, eye, and ovary. An EST has been isolated from an eye tissue library.
Synonyms MTNR1B
Reference Data
Protein Categories Endocrine and metabolic diseases, GPCR, Intracellular Proteins, Membrane Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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