OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Myelin Basic Protein (MBP) Chicken Polyclonal Antibody

Be the first to review this product
SKU
AP31809PU-N
Myelin Basic Protein (MBP) chicken polyclonal antibody, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated
  $825.00
2 Weeks*
Bulk/Customize

View other "Myelin Basic Protein or NP_001020252" antibodies

Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution Western Blot.
Immunocytochemistry.
Immunohistochemistry.
Recommended Dilutions:
1/2000-1/5000 for Western Blots.
1/1000-1/2000 for Immunohistochemstry and Immunocytochemistry using 2% paraformaldehyde-fixed tissues or cells.
Quality Control: This antibody was analyzed by Immunohistochemistry (at a 1/2000 dilution) using Fluorescein-labeled Goat anti-Chicken IgY (1/500 dilution, Cat.-No AP31795FC-N) as the secondary reagent.
Reactivity Human, Mouse
Antibody Host Chicken
Isotype IgY
Clonality Polyclonal
Immunogen Synthetic peptide KLH conjugated corresponding to a region of the MBP gene product shared between the Human (NP_002376) and Mouse (NP_034907) sequences.
After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks, and then affinity-purified using a peptide column.
Specificity Recognizes Myelin Basic Protein (MBP).
Buffer 10mM PBS, pH 7.2
State: Aff - Purified
State: Liquid purified (filter sterilized) IgY fraction
Preservative: 0.02% (w/v) Sodium Azide
Concentration lot specific
Purification Affinity Chromatography using a peptide column
Conjugation Unconjugated
Storage Store undiluted in the dark at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name myelin basic protein
Database Link
Background The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
Human Myelin Basic Protein (MBP) is a 20,115 dalton protein (186 amino acids) found in myelin of the CNS and PNS. Expressed as an intracellular protein by oligodendrocytes and Schwann cells, MBP aids in the compaction and stability of myelin.
Synonyms MBP
Reference Data
Protein Categories Chemokines, Intracellular Proteins
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Edaravone Protects Against Cuprizone-Induced Demyelination in Rats by Modulating TNF-α/NF-ĸB/NLRP3 Signaling and the Kynurenine Pathway
Mahmoud, Helal, El-Sherbiny et al
Eur J Pharmacol (2025)
Cited by 3
AI Summary: OriGene’s anti-MBP antibody (Cat No: AP31809PU-N) was used in this study to detect myelin basic protein, enabling the assessment of remyelination in rat brain tissue following edaravone treatment.
Snippet: eval using the heating method, followed by blocking with peroxidase. Primary antibodies against MBP (1:1000, pH = 7.2;OriGene Technologies, Inc. Cat No: AP31809PU-N), OLIG2 (1:500, pH = 9;Sigma-Aldrich, Millipore. Cat No: AB9610), QUIN (1:500, pH = 9;Immusmol SAS, France, Ref: IS002), and Anthra (1:50, pH = 6;Immusmol SAS, France, Ref: IS013) were appl
IHC
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products