KCNN4 (227-239) Goat Polyclonal Antibody
$595.00
3 Weeks*
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | Immunohistochemistry on Paraffin Sections: 3.75 - 7.5 µg/ml. |
| Reactivity | Bovine, Canine, Human, Rabbit |
| Antibody Host | Goat |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide from positions 227-239 of human KCNN4 (NP_002241.1) |
| Specificity | This antibody reacts to Potassium Intermediate/Small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (Kcnn4) at aa 227-239. |
| Buffer | Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purfied Ig fraction |
| Concentration | lot specific |
| Purification | Immunoaffinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | potassium calcium-activated channel subfamily N member 4 |
| Database Link | |
| Background | Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin. |
| Synonyms | KCNN4, IK1, IKCA1, KCA4, SK4, KCa3.1, Putative Gardos channel |
| Note | The Kcnn4 synonym, IK1, also is used to describe the cardiac inward rectifier current. |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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