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Tfam (C-term) Rabbit Polyclonal Antibody

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SKU
AP26439SU-N
Tfam (C-term) rabbit polyclonal antibody, Serum
Size:
100 ul
Conjugation:
Unconjugated
  $540.00
3 Days*
Bulk/Customize

View other "Tfam or NP_033386.1" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution Western blot: 1/2000.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen Native recombinant Mouse TFAM protein with C-terminal 6-His tag
Specificity Specific for the ~24 kDa TFAM protein.
Buffer State: Serum
State: Liquid serum
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name transcription factor A, mitochondrial
Database Link
Background Mitochondrial Transcription Factor A (TFAM) is a key activator of mitochondrial (mt) DNA transcription as well as a participant in mitochondrial genome replication. mtDNA is highly susceptible to oxidative stress leading to mitochondrial dysfunction. Overexpression of TFAM has been implicated in the amelioration of age dependent impairment of brain functions through the prevention of ox idative stress and mitochondrial dysfunction in microglia (Hayashi et al., 2008). More recently, TFAM overexpression has been shown to potentially reduce oxidative stress in motor neurons and delay onset of amyotrophic lateral sclerosis (ALS) in ALS model mice (Morimoto et al., 2012).
Synonyms TCF6L2, MtTF1, TCF-6
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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