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NF-kB p65 (RELA) pSer468 Rabbit Polyclonal Antibody

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SKU
AP26421AF-N
NF-kB p65 (RELA) pSer468 rabbit polyclonal antibody, Azide Free
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
2 Weeks*
Bulk/Customize

View other "RELA or NP_001138610.1" antibodies

Specifications
Specifications
Product Data
Application ELISA
Recommended Dilution ELISA: The antibody (approx. 1:50,000 -1:120,000 diluted) can detect the serine 468 phosphorylated NF-κB p65 peptide coated on ELISA plate at 100ng/well.
Reactivity Human, Mouse
Antibody Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide derived from Serine 468 phosphorylated NF-κB p65, conjugated with KLH
Specificity This antibody is reactive to the synthetic NF-κB -p65 peptide (FTDLASpVDNSE) with Mouse, Human and other species with
consensus serine 468 phosphorylated NF-κB -p65 peptide.
Buffer State: Azide Free
State: Lyophilized Ig fraction
Purification Protein G affinity
Conjugation Unconjugated
Storage Store lyophilized at 2-8°C for 6 month or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Gene Name RELA proto-oncogene, NF-kB subunit
Database Link
Background NF-κB (nuclear factor kappa-light-chainenhancer of activated B cells) is a transcription factor that controls the transcription of many genes that are associated with immuno-response, antiapoptosis, neuroplasticity and memory. There are five NF-κB proteins in mammals: RelA(NF-κB-p65), RelB, c-Rel, NF-κB (NF-κB-p105), and NF-κB2 (NF- κB-p100). They form a variety of homodimers and heterodimers, each of which activates its own distinctive set of genes. P65 has been shown to be involved with DNA binding. The phosphorylation of p65 at Ser468 is inducible by TNF. The phosphorylation mediates p65 ubiquitination and the termination of related gene expression.
Synonyms NF kappa B p65, NFkB p65, Transcription factor p65, Rel A, NFKB3
Reference Data
Protein Categories Cytokines, Growth Factors, Immune system diseases, Intracellular Proteins, Transciption Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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