ICAM1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, IHC, IP, WB |
|---|---|
| Recommended Dilution | Immunohistochemistry on frozen sections. Immunoprecipitation. Western blot. Immuhnoassay. The typical starting working dilution for Immunhistology and Western blot is 1:10. For selection of the most useful dilution in a given situation a test staining with cells or tissue known to express the antigen should be performed. To this end a small fresh skin biopsy can be incubated for 4 hours with TNF-alpha (1 ng/ml), IL-1 (100 U/ml) or LPS (1 µg/ml) in tissue culture medium at 37°C. |
| Reactivity | Human, Monkey |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Specificity | The antibody reacts with both intact human ICAM-1, CD54 and with soluble human ICAM-1. |
| Buffer | PBS Label: Biotin State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide |
| Concentration | lot specific |
| Purification | Protein A |
| Conjugation | Biotin |
| Storage | Store at 2 - 8 °C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | intercellular adhesion molecule 1 |
| Database Link | |
| Background | ICAM-1 (intercellular adhesion molecule) has 7 potential N-linked glycosylation sites. It is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). |
| Synonyms | ICAM-1 |
| Reference Data | |
| Protein Categories | Allergies and autoimmune diseases, CD Markers, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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