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Aggf1 Rabbit Polyclonal Antibody

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SKU
AP26374PU-N
Aggf1 rabbit polyclonal antibody, Purified
Size:
100 ug
Conjugation:
Unconjugated
  $795.00
2 Weeks*
Bulk/Customize

View other "Aggf1 or NP_079906.2" antibodies

Specifications
Specifications
Product Data
Application ELISA, IHC, IP, WB
Recommended Dilution Immunohistochemistry on frozen sections: The typical starting working dilution is 1:10.
Immunohistochemistry on paraffin sections: The typical starting working dilution is 1:10.
Immunoassays.
Immunoprecipitation.
Western blot: The typical starting working dilution is 1:10.
Reactivity Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Specificity The polyclonal antibody reacts with mouse VG5Q, a 84 kDa protein.
Buffer PBS
State: Purified
State: Liquid 0.2 µm filtered Ig fraction
Stabilizer: 0.1% bovine serum albumin
Preservative: 0.02% sodium azide
Concentration lot specific
Purification Protein A
Conjugation Unconjugated
Storage Store at 2 - 8 °C.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name angiogenic factor with G patch and FHA domains 1
Database Link
Background

VG5Q functions as an angiogenic factor in promoting angiogenesis and suppression of VG5Q expression inhibits vessel formation. Angiogenic factors are critical to the initiation of angiogenesis and maintenance of the vascular network. Angiogenesis has an essential role in pathological conditions such as cancer and various ischaemic and inflammatory diseases.
VG5Q can bind to endothelial cells and promote cell proliferation, suggesting that the protein may act in an autocrine fashion. VG5Q interacts with TWEAK (also known as TNFSF12), another secreted angiogenic factor.
VG5Q shows strong expression in blood vessels and is secreted when vessel formation is initiated. VG5Q protein was detected mostly in the cytoplasm and around the nuclei of human microvascular endothelial cells (HMVECs). Furthermore VG5Q is detected in human umbilical vein endothelial cells (HUVECs), human heart fibroblast (HHF) and ovarian cancer cells (OV-3), but low expression was detected in kidney cancer cells (RP-45), HeLa Cells and bladder cancer cells.
Synonyms GPATC7, GPATCH7
Reference Data
Protein Categories Intracellular Proteins, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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