Il6 Rabbit Polyclonal Antibody

CAT#: AP26368PU-N

Il6 rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, FN, WB
• Recommended Dilution: Immunassays.
  Western blot: The typical starting working dilution is 1/10.
  Functional assays: Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added.
• Reactivities: Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Specificity:

  The antibody reacts with natural and recombinant mouse interleukin 6 (IL-6) as assessed by ELISA.
  The antibody inhibits the biological activity of natural and recombinant Mouse IL-6 as determined with the B9 cell bio-assay.
  The antibody cross-reacts with natural Rat IL-6.

• Formulation: PBS
  State: Purified
  State: Liquid 0.2 µm filtered Ig fraction
  Stabilizer: 0.1% BSA
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Protein A Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: interleukin 6
• Database Link:
  Entrez Gene 16193 Mouse
  UniProt ID P08505
• Background: IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and hematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas.
• Synonyms: IL-6, Interferon beta-2, IFNB2, B-cell stimulatory factor 2, BSF-2, CDF