Fbxl3 (1-5) Rabbit Polyclonal Antibody
$430.00
2 Weeks*
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | Western blot: 1:500~1:1000. |
| Reactivity | Mouse |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Peptide sequence around aa.1~5 derived from mouse FBXL3 |
| Specificity | This antibody detects endogenous levels of total FBXL3 protein. |
| Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Affinity-chromatography using epitope-specific peptide |
| Conjugation | Unconjugated |
| Storage | Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | F-box and leucine-rich repeat protein 3 |
| Database Link | |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. |
| Synonyms | FBL3A, FBXL3A |
| Note | Molecular weight: 49 kDa |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
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Citations
Fbxl3 deletion mitigates myopathy in mdx mice through upregulation of myogenin
Chen, He, Si et al
Biochem Biophys Res Commun (2025) 776, 152220 DOI: 10.1016/j.bbrc.2025.152220
Chen, He, Si et al
Biochem Biophys Res Commun (2025) 776, 152220 DOI: 10.1016/j.bbrc.2025.152220
Cited by 1
AI Summary: OriGene contributed to this study by providing the FBXL3 antibody (AP26069PU-N), which was used in Western blot analyses to assess FBXL3 protein levels in muscle tissues.
Snippet: stern blot Western blot was performed as described previously [14]. FBXL3 antibody was from OriGene (AP26069PU-N, 1:1000 dilution). Antibodies against GAPDH (2118s, 1:5000 dilution) were from Cell Signaling Technology. 2.7. Productio
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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