Suppressor of Fused (SUFU) pSer342 Rabbit Polyclonal Antibody

SKU
AP26040PU-N
Suppressor of Fused (SUFU) pSer342 rabbit polyclonal antibody, Aff - Purified
  $430.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution Western blot: 1:500 - 1:1000.
Reactivity Human
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of Serine 342 derived from Human Sufu
Specificity This antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity-chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name SUFU negative regulator of hedgehog signaling
Database Link
Background SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700).
Synonyms Suppressor of fused homolog
Note Molecular weight: 54 kDa
Reference Data
Protein Categories Cancer: Brain and CNS, Intracellular Proteins
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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