Foxp3 (C-term) Goat Polyclonal Antibody
$565.00
5 Days*
Specifications
| Product Data | |
| Application | ELISA, IHC |
|---|---|
| Recommended Dilution | Peptide ELISA: 1/4000. Immunohistochemistry: 2-4 µg/ml. In paraffin embedded Mouse Thymus shows nuclear staining in some patches of thymocytes. |
| Reactivity | Mouse, Rat |
| Antibody Host | Goat |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence from the C Terminus of the protein sequence according to NP_473380.1. |
| Specificity | Recognizes FOXP3 / Scurfin (Mouse). |
| Buffer | Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer. State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | forkhead box P3 |
| Database Link | |
| Background | FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells. |
| Synonyms | Forkhead box protein P3, IPEX, JM2, Scurfin |
| Reference Data | |
| Protein Categories | ADC Targets, Cytokines, Diabetes, Growth Factors, Immune system diseases, Intracellular Proteins, Transciption Factors |
Reviews
Documents
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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