TLR3 (514-657) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | Immunocytochemistry. Immunofluorescence: 1/100 - 1/200. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 1/1000 - 1/10000. |
| Reactivity | Bovine, Feline, Guinea Pig, Human, Monkey, Mouse, Porcine, Rabbit, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | TLR3 antibody was raised against recombinant protein fragment containing a sequence corresponding to a region within amino acids 514 and 657 of TLR3. |
| Specificity | This antibody reacts to Toll-like Receptor 3 (TLR3) at aa 514-657. |
| Buffer | 0.1 M Tris-glycine, pH 7.0 containing 10% Glycerol and 0.01% Thimerosal State: Aff - Purified State: Liquid purfied Ig fraction |
| Concentration | lot specific |
| Purification | Immunoaffinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | toll like receptor 3 |
| Database Link | |
| Background | TLR3 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. |
| Synonyms | Toll-like receptor 3 |
| Reference Data | |
| Protein Categories | CD Markers, Chemokines, Cytokines, Intracellular Proteins, Membrane Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Toll-like receptor signaling pathway |
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