DAP12 (TYROBP) (Internal) Goat Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, IHC |
|---|---|
| Recommended Dilution | ELISA. Immunohistochemistry on Paraffin Sections: 3 - 6 µg/ml. |
| Reactivity | Bat, Canine, Equine, Human, Monkey |
| Antibody Host | Goat |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide C-KQRITETESPYQE from an internal region of human TYROBP / DAP12 (NP_003323.1; NP_937758.1) |
| Specificity | This antibody reacts to Tyro Protein Tyrosine Kinase Binding Protein (TYROBP) at Internal region. |
| Buffer | Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Immunoaffinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | TYRO protein tyrosine kinase binding protein |
| Database Link | |
| Background | DAP12 is a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. |
| Synonyms | KARAP |
| Reference Data | |
| Protein Categories | Growth Factors, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Natural killer cell mediated cytotoxicity |
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