AIM2 (C-term) Goat Polyclonal Antibody

SKU AP22454PU-N

AIM2 (C-term) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC, WB
• Recommended Dilution: Peptide ELISA: 1/8000 (Detection Limit). ; Western Blot: 1-3 µg/ml. Approx 50+55kDa bands observed in lysates of Human WI-38 fibroblast after treatment with interferon beta (calculated MW of 39.0kDa according to NP_004824.1). ; The observed molecular weight corresponds to earlier findings in literature with different antibodies (Choubey et al., J. Interferon Cytokine Res. 2010 Jun;30(6):371-80. PMID: 20187776). ; Immunohistochemistry on Paraffin Sections: 4-6 µg/ml. In paraffin embedded Human Spleen shows nucleolar staining in some splenocytes.
• Reactivity: Human
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence from the C-Terminus of the protein sequence according to NP_004824.1.
• Specificity: This antibody detects AIM2 at C-term.
• Buffer: Tris saline, pH~7.3; State: Aff - Purified; State: Liquid purified Ig fraction; Stabilizer: 0.5% BSA; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: absent in melanoma 2
• Database Link:
  O14862
• Background: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon gamma induces expression of AIM2.
• Synonyms: PYHIN4

Reference Data