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SynCAM (CADM1) Goat Polyclonal Antibody

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SKU
AP21519PU-N
SynCAM (CADM1) goat polyclonal antibody, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
5 Days*
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View other "SynCAM or NP_001091987" antibodies

Specifications
Specifications
Product Data
Application ELISA, WB
Recommended Dilution Peptide ELISA: 1/16000 (Detection limit).
Western blot: 0.1-0.3 µg/ml. Approx 42kDa band observed in Mouse Heart lysates (Calculated MW of 45.8kDa according to Mouse NP_001020771.1).
Reactivity Bovine, Canine, Human, Mouse, Rat
Antibody Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence from the internal region of the protein sequence according to NP_055148.3; NP_001091987.1.
Specificity This antibody is expected to recognize both reported isoforms (NP_055148.3 and NP_001091987.1).
Buffer Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name cell adhesion molecule 1
Database Link
Background Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with binding with other cells or with the extracellular matrix. SynCAM belongs to immunoglobulin superfamily 4 and is involved in cell-cell adhesion. Loss of SynCAM is common in a number of cancers including lung, breast, prostate and meningioma. This loss of SynCAM in advanced stage cancers suggests a role in tumor invasion and/or metastasis. Also recent studies have shown that SynCAM suppresses induction of EMT (epithelial mesenchymal transition) via regulation of Rho GTPases.
Synonyms IGSF4, IGSF4A, NECL2, TSLC1, NECL-2, SgIgSF, TSLC-1
Reference Data
Protein Categories Cancer: Head and Neck, Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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