OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

CDC42 Binding Protein Kinase Beta (CDC42BPB) Rabbit Polyclonal Antibody

Be the first to review this product
SKU
AP20465PU-N
CDC42 Binding Protein Kinase Beta (CDC42BPB) rabbit polyclonal antibody, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated
  $495.00
7 Weeks*
Bulk/Customize

View other "CDC42 Binding Protein Kinase Beta or NP_006026" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution Western blot: 1/500 - 1/1000.
Immunohistochemistry on paraffin sections: 1/50 - 1/200.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Specificity This antibody detects endogenous levels of MRCKbeta protein.
(region surrounding Phe1665)
Buffer Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Purification Affinity chromatography (> 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size ~ 194 kDa
Gene Name CDC42 binding protein kinase beta
Database Link
Background Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.
Synonyms MRCK beta, KIAA1124, DMPK-like beta
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products