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Ephrin A1 (EFNA1) Rabbit Polyclonal Antibody

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SKU
AP20378PU-N
Ephrin A1 (EFNA1) rabbit polyclonal antibody, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated
  $495.00
7 Weeks*
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View other "Ephrin A1 or NP_004419" antibodies

Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution Western blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 70-120 of Human Ephrin-A1.
Specificity This antibody detects endogenous levels of Ephrin-A1 protein.
Buffer PBS, pH~7.2 with 50% Glycerol
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 0.02% Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size ~ 23 kDa
Gene Name ephrin A1
Database Link
Background The Eph subfamily represents the largest group of receptor protein kinases identified to date. There is increasing evidence that Eph family members are involved in central nervous system function and in development. Ligands for Eph receptors include ephrin-A1 (LERK-1/B61), identified as a ligand for the EphA2 (Eck) receptor; ephrin-A2 (ELF-1), identified as a ligand for the EphA3 and EphA4 (Sek) receptors; ephrin-A3 (LERK-3), identified as a ligand for EphA5 (Ehk1) and EphA3 (Hek) receptors; ephrin-A4 (LERK-4), identified as a ligand for the EphA3 receptor; ephrin-A5 (AL-1), identified as a ligand for EphA5 (REK7); ephrin-B1 (LERK-2), identified as a ligand for the EphB1 (Elk) and EphB2 (Cek5) receptors; ephrin-B2 (LERK-5), identified as a ligand for the EphB1, EphB3 (Cek10) and EphB2 receptors; and ephrin-B3 (LERK-8), identified as a ligand for EphB1.
Synonyms EFNA1, LERK-1, EPLG1, LERK1, TNFAIP4
Reference Data
Protein Categories Secreated Proteins
Protein Families Druggable Genome
Protein Pathways Axon guidance
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Documents
Resources

file-alt Citations

Long Noncoding RNA GMAN, Up-regulated in Gastric Cancer Tissues, Is Associated With Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS
Zhuo, Liu, Li et al
Gastroenterology (2019) 156 (3), 676-691.e11 DOI: 10.1053/j.gastro.2018.10.054
AI Summary: In this study, OriGene’s anti-ephrin A1 antibody was used for immunohistochemistry analysis of tissue arrays to assess ephrin A1 protein expression in gastric cancer tissues, helping to elucidate the role of GMAN lncRNA in cancer metastasis.
Snippet: Immunohistochemistry and Tissue Array Analysis Paraffin-embedded tissues were sectioned, stained with H&E, and imaged with a microscope (Olympus). The tissue array (TA) was obtained from the Sir Run Shaw Hospital, Zhejiang University School of Medicine. The TA was stained by using anti-ephrin A1 antibody (OriGene, 1:100), counterstained with hematoxylin, and analyzed with a Panoramic MIDI TA scanner (3D HISTECH). …
IHC
Long Non-coding RNA GMAN, Upregulated in Gastric Cancer Tissues, is Associated with Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS
Zhuo, Liu, Li et al
Gastroenterology (2018)
AI Summary: OriGene’s anti-ephrin A1 antibody was used in this study to detect ephrin A1 protein levels in tissue samples, facilitating the investigation of its role in gastric cancer metastasis.
Snippet: Shaw Hospital, Zhejiang University School of Medicine. The TA was stained by using anti-ephrin A1 antibody (OriGene, 1:100), counterstained with hemotoxylin and analyzed by Pannoramic MIDI TA scanner (3D HISTECH). Further details are available in
IHC
Showing 1-2 of 2 papers.
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