PARD3 (C-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Clone Name | RB21955 |
|---|---|
| Application | FC, IHC, WB |
| Recommended Dilution | WB 1:1000 IHC-P 1:50~100 FC 1:10~50 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide selected from the C-terminal region of human PARD3 |
| Specificity | This PARD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1329-1356 amino acids from the C-terminal region of human PARD3. |
| Buffer | PBS with 0.09% (W/V) sodium azide State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 151423 kDa |
| Gene Name | par-3 family cell polarity regulator |
| Database Link | |
| Background | PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain. |
| Synonyms | PARD-3, PAR-3, PAR3A, PAR3-alpha, ASIP |
| Reference Data | |
| Protein Pathways | Adherens junction, Chemokine signaling pathway, Endocytosis, Neuroactive ligand-receptor interaction, Tight junction |
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