PARD3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP18146PU-N

PARD3 (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of PARD3 Antibody (C-term) in mouse stomach tissue lysates (35ug/lane). PARD3 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human PARD3
• Specificity: This antibody reacts to PARD3.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: par-3 family cell polarity regulator
• Database Link:
  Entrez Gene 93742 MouseEntrez Gene 56288 Human
  UniProt ID Q8TEW0
• Background: PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain.
• Synonyms: PARD-3, PAR-3, PAR3A, PAR3-alpha, ASIP

Reference Data

• Protein Pathways: Adherens junction, Chemokine signaling pathway, Endocytosis, Neuroactive ligand-receptor interaction, Tight junction