KMT5C (Center) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | FC, WB |
|---|---|
| Recommended Dilution | WB:1/1000, FC:1/10-50 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide selected from the Center region of human SUV420H2 |
| Specificity | This SUV4-20H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-220 amino acids of human SUV4-20H2. |
| Buffer | PBS with 0.09% (W/V) sodium azide State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 52.1 kDa |
| Gene Name | lysine methyltransferase 5C |
| Database Link | |
| Background | SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). |
| Synonyms | Lysine N-methyltransferase 5C |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Lysine degradation |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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