FKBP10 (N-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | FC, IHC, WB |
|---|---|
| Recommended Dilution | WB:1/1000, IHC-P:1/50-200, FC:1/10-50 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 65~94 amino acids from the N-terminal region of human FKBP10. |
| Specificity | This FKBP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-87 amino acids of human FKBP10. |
| Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 64.2 kDa |
| Gene Name | FK506 binding protein 10 |
| Database Link | |
| Background | The protein belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase family. It is located in endoplasmic reticulum and acts as molecular chaperones. |
| Synonyms | FK506-binding protein 10, Immunophilin FKBP65, PPIase FKBP10, Rotamase |
| Reference Data | |
| Protein Families | Druggable Genome |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
FK506-Binding Protein 10, a Potential Novel Drug Target for Idiopathic Pulmonary Fibrosis
Staab-Weijnitz, Fernandez, Knüppel et al
Am J Respir Crit Care Med (2015) 192 (4), 455-67 DOI: 10.1164/rccm.201412-2233OC
Staab-Weijnitz, Fernandez, Knüppel et al
Am J Respir Crit Care Med (2015) 192 (4), 455-67 DOI: 10.1164/rccm.201412-2233OC
AI Summary: In this study, OriGene’s FKBP10 siRNA (SR304425) and FKBP10 antibody (TA500494) were used to knock down FKBP10 expression and detect FKBP10 protein, respectively, enabling the researchers to assess FKBP10’s role in collagen secretion and its potential as a drug target for idiopathic pulmonary fibrosis.
Showing 1-1 of 1 papers.
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