FGF18 (N-term) Rabbit Polyclonal Antibody

SKU AP17367PU-N

FGF18 (N-term) rabbit polyclonal antibody

Product Data

• Application: WB
• Recommended Dilution: Western blot: 1:50 - 1:100.; ELISA: 1:1,000.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human FGF18
• Specificity: This antibody detects FGF18 at N-term.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: fibroblast growth factor 18
• Database Link:
  O76093
• Background: FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
• Synonyms: Fibroblast growth factor 18, FGF-18, zFGF5
• Note: Molecular weight: 23989 Da

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton