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ALS2 (C-term) Rabbit Polyclonal Antibody

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SKU
AP17102PU-N
ALS2 Antibody (C-term)
Size:
400 ul
Conjugation:
Unconjugated
  $645.00
2 Weeks*
Bulk/Customize

View other "ALS2 or NP_001129217" antibodies

Specifications
Specifications
Product Data
Clone Name RB18853
Application IHC, WB
Recommended Dilution WB 1:1000
IHC-P 1:50~100
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human ALS2
Specificity This ALS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2.
Buffer PBS with 0.09% (W/V) sodium azide
State: Liquid Ig fraction
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation Unconjugated
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 183634 kDa
Gene Name ALS2, alsin Rho guanine nucleotide exchange factor
Database Link
Background ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.
Synonyms ALS2CR6, KIAA1563
Note Molecular weight: 183666 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Amyotrophic lateral sclerosis (ALS)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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