COMT (N-term) Goat Polyclonal Antibody
$565.00
5 Days*
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | Peptide ELISA: Detection Limit Dilution: 1/4000. Western Blot: 0.3-1.0 µg/ml. Approx 26kDa plus 29kDa bands observed in Human Testis lysates (calculated MW of 30.0kDa according to NP_000745.1 and of 24.5kDa according to NP_009294.1). |
| Reactivity | Canine, Human, Mouse, Rat |
| Antibody Host | Goat |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence GDTKEQRILNHVLQC, from the N-Terminus of the protein sequence |
| Specificity | This antibody is expected to recognise both reported isoforms. Variants (NP_000745.1, NP_001128633.1 and NP_001128634.1) encode the same isoform. |
| Buffer | Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer. State: Aff - Purified State: Liquid purified IgG fraction. |
| Concentration | lot specific |
| Purification | Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | catechol-O-methyltransferase |
| Database Link | |
| Background | Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. |
| Synonyms | Catechol O-methyltransferase |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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