PHLPP (PHLPP1) (N-term) Rabbit Polyclonal Antibody

CAT#: AP14678PU-N

PHLPP (PHLPP1) (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-PHLPP1 Antibody (N-term) in K562 cell line lysates (35ug/lane).PHLPP1 (arrow) was detected using the purified Pab (1:60dilution).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PHLPP1.
• Specificity: This antibody reacts to PHLPP1.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: PH domain and leucine rich repeat protein phosphatase 1
• Database Link:
  Entrez Gene 23239 Human
  UniProt ID O60346
• Background: PHLPP1 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes.
• Synonyms: PHLPP, PLEKHE1, SCOP, KIAA0606