PHLPP (PHLPP1) (N-term) Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/50 - 1/100. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | Ig |
| Clonality | Polyclonal |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PHLPP1. |
| Specificity | This antibody reacts to PHLPP1. |
| Buffer | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | PH domain and leucine rich repeat protein phosphatase 1 |
| Database Link | |
| Background | PHLPP1 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. |
| Synonyms | PHLPP, PLEKHE1, SCOP, KIAA0606 |
| Reference Data | |
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