MUSK Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Clone Name | RB14743 |
|---|---|
| Application | FC, IF, WB |
| Recommended Dilution | IF 1:10~50 WB 1:1000 FC 1:10~50 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | This antibody is generated from rabbits immunized with human recombinant MUSK protein. |
| Specificity | This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein. |
| Buffer | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 97056 kDa |
| Gene Name | muscle associated receptor tyrosine kinase |
| Database Link | |
| Background | MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK. |
| Synonyms | Muscle-specific kinase receptor |
| Reference Data | |
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