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Igfbp3 Rabbit Polyclonal Antibody

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SKU
AP14347PU-N
IGFBP3 Antibody (S183)
Size:
400 ul
Conjugation:
Unconjugated
  $645.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB:1/1000
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S183 of human IGFBP3.
Specificity This IGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from human IGFBP3.
Buffer PBS with 0.09% (W/V) sodium azide
State: Aff - Purified
State: Liquid purified Ig
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 31.7 kDa
Gene Name insulin like growth factor binding protein 3
Database Link
Background IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. This protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
Synonyms IGFBP-3, IGF-BP3, IBP3, Insulin-like growth factor-binding protein 3, IGF-binding protein 3, IBP-3
Reference Data
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Documents
Resources

file-alt Citations

Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus
Kazezian, Gawri, Haglund et al
Sci Rep (2015) 5, 15662 DOI: 10.1038/srep15662
Cited by 90
AI Summary: In this study, OriGene products—including the IFIT3 (Cat# SC119874) and IGFBP3 (Cat# SC119874) qPCR primers—were used to validate gene expression changes identified in degenerative human annulus fibrosus tissue, supporting the discovery of interferon signalling pathway involvement in disc degeneration.
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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