TASP1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP11325PU-N

TASP1 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of TASP1 (C-term) polyclonal antibody in mouse kidney tissue lysates. TASP1 (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with hTASP1-C-term, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/1,000.
  Immunohistochemistry: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-395 amino acids from the C-terminal region of human TASP1.
• Specificity: This antibody is specific to TASP1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: taspase 1
• Database Link:
  Entrez Gene 55617 Human
  UniProt ID Q9H6P5
• Background: TASP1 is an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor.
• Synonyms: Threonine aspartase 1, C20orf13
• Note: Calculated MW: 44455 Da