PPP1R14A (Isoform alpha) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF |
|---|---|
| Recommended Dilution | Immunofluorescence: 1/100 - 1/200. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthesized non-phosphopeptide derived from human CPI17α around the phosphorylation site of threonine 38 (R-V-TP-V-K) |
| Specificity | CPI17α antibody detects endogenous levels of total CPI17α protein. |
| Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | protein phosphatase 1 regulatory inhibitor subunit 14A |
| Database Link | |
| Background | PKC potentiated inhibitor protein-17 is a 17kDa protein. Expressed in smooth muscles and neuronal cells, CP117 is a myosin phosphatase inhibitor protein. Phosphorylation of CP117 at Thr38 enhances its inhibitory effect by 100 fold. Once phosphorylated, CP117 inhibits PP1c and MLCP holoenzyme activity. |
| Synonyms | Protein phosphatase 1 regulatory subunit 14A, CPI-17, CPI17, PPP1INL |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Vascular smooth muscle contraction |
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