ANKRD32 (SLF1) (78-91) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | WB: 1:500- 1:2,000 ELISA: 1:10,000 - 1:50,000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 75-100 of Human Hallen. Hallen is a novel BRCT domain containing protein. |
| Specificity | This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase. |
| Buffer | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 Stabilizer: None Preservative: 0.01% (w/v) Sodium Azide |
| Concentration | 1.33 mg/mL - lot specific |
| Purification | Immunoaffinity chromatography |
| Conjugation | Unconjugated |
| Storage | Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. |
| Stability | Expiration date is one (1) year from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | SMC5-SMC6 complex localization factor 1 |
| Database Link | |
| Background | Anti-HALLEN plays a role in the DNA damage response pathway by regulating post replication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links and DNA double-strand breaks sites on chromatin during DNA repair in response to stalled replication forks. Anti-HALLEN promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions. Anti-Hallen Antibody is useful for researchers interested in DNA damage and repair. |
| Synonyms | rabbit anti-HALLEN antibody, Ankyrin repeat domain-containing protein 32, ANKRD32, cDNA FLJ57532, BRCT domain-containing protein 1, BRCTD1 antibody, Smc5/6 localization factor 1, SLF1, SMC5-SMC6 Complex Localization Factor 1 |
| Note | This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown. |
| Reference Data | |
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