VAP1 (AOC3) (712-724) Goat Polyclonal Antibody
$535.00
3 Weeks*
Specifications
| Product Data | |
| Application | ELISA, IHC |
|---|---|
| Recommended Dilution | ELISA: 1/64000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml. |
| Reactivity | Hamster, Human, Mouse, Rat |
| Antibody Host | Goat |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide from an internal region of human AOC3 |
| Specificity | This antibody reacts to Copper Amine Oxidase (AOC3) at aa 712-724. |
| Buffer | Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Immunoaffinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | amine oxidase, copper containing 3 |
| Database Link | |
| Background | VAP1, upregulated in response to inflammation, is a cell adhesion protein that participates in lymphocyte recirculation, by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells, in an L selectin independent fashion. VAP1 also displays a monoamine oxidase activity, catalyzing the deamination of methylamine to produce formaldehyde. Upregulation of VAP1 has been reported in Alzheimer's disease, where increased levels of formaldehyde are responsible for b amyloid cross linkage and plaque formation, significantly contributing to the pathogenesis of this disease. |
| Synonyms | HPAO |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
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| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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