SMRC2 (SMARCC2) Rabbit Polyclonal Antibody

SKU
AP06744PU-N
SMRC2 (SMARCC2) rabbit polyclonal antibody, Aff - Purified
  $495.00
7 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, WB
Recommended Dilution Western blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Reactivity Human, Mouse
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 350-402 of Human BAF170.
Specificity This antibody detects endogenous levels of BAF170 protein.
(region surrounding Met388)
Buffer Phosphate buffered saline (PBS), pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration 1.0 mg/ml
Purification Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size ~ 170 kDa
Gene Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Database Link
Background The SWI/SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF1 or SNF2α) and Brg-1 (also designated SNF2 or SNF2β) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
Synonyms BAF170; CRACC2; Rsc8
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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