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MEK6 (MAP2K6) Rabbit Polyclonal Antibody

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SKU
AP06705PU-N
MEK6 (MAP2K6) rabbit polyclonal antibody, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated
  $495.00
7 Weeks*
Bulk/Customize

View other "MAP2K6 or NP_002749.2" antibodies

Specifications
Specifications
Product Data
Application IF, IHC
Recommended Dilution IHC:1/50-200, IF:1/50-200
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids N-terminus of Human MEK-6.
Specificity This antibody detects endogenous levels of MEK-6 protein.
(region surrounding Gln3)
Buffer Phosphate buffered saline (PBS), pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration 1.0 mg/ml
Purification Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size ~ 37 kDa
Gene Name mitogen-activated protein kinase kinase 6
Database Link
Background A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.
Synonyms MAPKK 6, MAPK/ERK kinase 6, SAPKK3, MEK6, MKK6, MAP kinase kinase 6
Reference Data
Protein Categories Cytokines, Enzyme: Kinases, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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