TL1A (TNFSF15) Rabbit Polyclonal Antibody
$495.00
7 Weeks*
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | IF:1/50-200 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide, corresponding to amino acids 111-160 of Human VEGI. |
| Specificity | This antibody detects endogenous levels of VEGI protein. (region surrounding Phe141) |
| Buffer | Phosphate buffered saline (PBS), pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide |
| Concentration | 1.0 mg/ml |
| Purification | Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 25 kDa |
| Gene Name | tumor necrosis factor superfamily member 15 |
| Database Link | |
| Background | Vascular endothelial cell growth inhibitor (VEGI also known as TNFRSF15 or TL1), a member of the TNF superfamily, has a signaling pathway similar to TNF and is most likely a multifunctional cytokine. VEGI is found in brain, reproductive, and late developmental stage embryonic tissues and expressed predominantly in endothelial cells. VEGI is an angiogenesis inhibitor of the TNF family and functions in part by directly inhibiting endothelial cell proliferation.VEGI may act as an autocrine factor to induce apoptosis in endothelial cells via activation of multiple signaling pathways, including stress protein kinases as well as certain caspases. |
| Synonyms | TL1, TL1A, VEGI |
| Reference Data | |
| Protein Categories | Cytokines, Immune system diseases, Intracellular Proteins, Secreated Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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