GANP (MCM3AP) Rabbit Polyclonal Antibody
$495.00
7 Weeks*
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | IHC:1/50-200 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide, corresponding to amino acids 1841-1890 of Human GANP. |
| Specificity | This antibody detects endogenous levels of GANP/MCM3AP protein. (region surrounding Glu1872) |
| Buffer | Phosphate buffered saline (PBS), pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 0.05% Sodium azide |
| Concentration | 1.0 mg/ml |
| Purification | Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 218 kDa |
| Gene Name | minichromosome maintenance complex component 3 associated protein |
| Database Link | |
| Background | Minichromosome maintenance protein 3 (MCM3) is a protein essential for the initiation of DNA replication. MCM3-associated protein (MCM3AP), also known as GANP or MAP80, is a 1980 amino acid protein which binds to MCM3. MCM3AP is an acetyltransferase that acetylates MCM3, thereby playing an indirect role in DNA replication. MCM3AP is also believed to be involved in the nuclear localization of MCM3. Localized to the nucleus and the cytoplasm, GANP (MCM3AP) is thought to have phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center regions. MCM3AP contains a nuclear localization signal, a coiled-coil structure and four LXXLL motifs. |
| Synonyms | GANP, KIAA0572, MAP80 |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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