PPAR gamma (PPARG) (Isoform 1) Rabbit Polyclonal Antibody

SKU
AP05657PU-N
PPAR gamma (PPARG) (Isoform 1) rabbit polyclonal antibody, Purified
  $580.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application ELISA
Recommended Dilution ELISA: 1:8000 - 1:32000.
Reactivity Canine, Duck, Guinea Pig, Hamster, Human, Mink, Monkey, Mouse, Rabbit, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to amino acids 255 - 268 of human PPAR gamma isoform 1.
Specificity This antibody detects human peroxisome proliferator-activated receptor gamma (PPARG).
Buffer Phosphate buffered saline pH7.2 containing 0.01% Sodium Azide (NaN3)
State: Purified
State: Liquid purified IgG
Concentration lot specific
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name peroxisome proliferator activated receptor gamma
Database Link
Background PPARG is a member of the nuclear hormone receptor subfamily of transcription factors. Upon activation, PPARG forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARG is principally involved in the cellular assimilation of lipids, with key roles in adipocyte differentiation and adipogenesis.
Two alternatively spliced isoforms of PPARG exist, termed PPARG1 and PPARG2, which are identical except for an additional 30 amino acids at the N-terminus of PPARG2. This results in a predominant adipocyte localisation for PPARG2, whilst PPARG1 is ubiquitously expressed. PPARG has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer.
Synonyms PPARG, NR1C3
Reference Data
Protein Categories Cancer: Endocrine, Endocrine and metabolic diseases, Growth Factors, Intracellular Proteins, Transciption Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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