OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

SPHK2 (Long Form) Rabbit Polyclonal Antibody

Be the first to review this product
SKU
AP05214PU-N
SPHK2 (Long Form) rabbit polyclonal antibody, Purified
Size:
100 ug
Conjugation:
Unconjugated
  $1,055.00
5 Days*
Bulk/Customize

View other "SPHK2 or NP_064511" antibodies

Specifications
Specifications
Product Data
Application ELISA, WB
Recommended Dilution ELISA.
Western blot: 1 - 5 µg/ml.
Reactivity Human
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide derived from the N-terminal extension of the Sphk2-L protein.
Specificity This antibody reacts to Sphingosine Kinase 2 (Long Form).
Buffer Phosphate buffered saline with 0.08% sodium azide
State: Purified
State: Liquid purified Ig
Concentration lot specific
Conjugation Unconjugated
Storage The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name sphingosine kinase 2
Database Link
Background The long form of sphingosine kinase 2 (Sphk2-L) is a speciesspecific isoform of the Sphk2 enzyme expressed in human but not in mouse. It is an N-terminal extended form of Sphk2, extended by 36 amino acids. It functions as expected, catalyzing the formation of sphingosine 1-phosphate from sphingosine, however it appears to have a decreased ability to inhibit DNA synthesis as compared to Sphk2-S (short form of Sphk2). Under normal cellular conditions, Sphk2-L does not appear to inhibit DNA synthesis, but under serum deprivation, SphK2-L translocates to the nucleus and accumlates. This accumlation may be involved in the cessation of cell proliferation or apoptosis depending on the cell type.
Synonyms SK2, SPHK2
Reference Data
Protein Categories Cytokines, Growth Factors, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Metabolic pathways, Sphingolipid metabolism, VEGF signaling pathway
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products