Sphingomyelin Synthase 2 (SGMS2) Rabbit Polyclonal Antibody
![Western blot on human brain lysate (10 ug/lane) using antibody to Sphingomyelin Synthase 2 (0.5 ug/ml). Lane A] 1 ug/ml antibody alone, lane B] antibody plus 3 ug blocking peptide. Blot was developed with Pierce's Super Sytem West Femto - 1 minute exposure.](https://cdn.origene.com/catalog/product/assets/images/antibody/acris/ap05208pu-n-1-w.jpg?width=700&height=700&store=america&image-type=image "Western blot on human brain lysate (10 ug/lane) using antibody to Sphingomyelin Synthase 2 (0.5 ug/ml). Lane A] 1 ug/ml antibody alone, lane B] antibody plus 3 ug blocking peptide. Blot was developed with Pierce's Super Sytem West Femto - 1 minute exposure.")
$1,055.00
5 Days*
Specifications
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | ELISA. Western Blot: 5 - 10 µg/ml. Positive Control: Brain, heart, kidney, liver, muscle and stomach. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide derived from the human sphingomyelin synthase 2 protein. |
| Specificity | This antibody reacts to Sphingomyelin Synthase 2. |
| Buffer | Phosphate buffered saline, pH 7.4 State: Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | sphingomyelin synthase 2 |
| Database Link | |
| Background | Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane. |
| Synonyms | Sphingomyelin synthase 2, SMS2 |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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