Bax (beta isoform) Sheep Polyclonal Antibody
$800.00
5 Days*
Specifications
| Product Data | |
| Application | IP |
|---|---|
| Recommended Dilution | Immunoprecipitation. Will NOT detect denatured protein by Western blot. |
| Reactivity | Mouse |
| Antibody Host | Sheep |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to amino acids 172 to 199 of the Bax beta protein |
| Specificity | This antibody reacts to Bax-beta. |
| Buffer | Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | BCL2-associated X protein |
| Database Link | |
| Background | Bax-beta is encoded by a 1.5 kb RNA species created by the retention of intron 5 in the bax mRNA transcript. The exon4/intron5 splice junction is evolutionarily conserved and is found in both the human and mouse bax coding regions. The 630 bp intron 5 contributes 60 amino acids to the Bax-beta protein before a stop codon is encountered during translation. The Bax-beta protein is 24 kDa in size and although it contains the BH1, BH2, and BH3 domains identical to Bax, it has a unique carboxyl terminus and does not have a hydrophobic transmembrane domain (Oltvai et al., 1993). Bax-beta mRNA has been found in many mouse tissues using RT-PCR. It is found co-expressed with Bax-alpha in lung, stomach, kidney, thymus, lymph node, bone marrow, pancreas, and spleen. Bax-beta mRNA was very abundant in brain and duodenum with almost no Bax-alpha mRNA detected in these tissues (Oltvai et al., 1993). |
| Synonyms | Apoptosis regulator BAX, BCL2L4, Bcl2-L-4 |
| Reference Data | |
| Protein Categories | Cancer: Gastrointestinal, Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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