Adarb1 Sheep Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | Western Blot: 1/1000. Positive Control: Rat Brain. |
| Reactivity | Rat |
| Antibody Host | Sheep |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | GST fusion protein containing aa 6-66 of the rat RED1 coding sequence |
| Specificity | This antibody recognizes ADAR2 (Adenosine Deaminase Acting on RNA 2). |
| Buffer | State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Antigen Immunoaffiinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 80.7 kDa |
| Gene Name | adenosine deaminase, RNA-specific, B1 |
| Database Link | |
| Background | RED 1 also called ADAR2 is involved in the editing of the messenger RNAs for glutamate receptor (GluR) subunits by siteselective adenosine deamination. It edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently. |
| Synonyms | DRADA2, RED1, RNA-editing enzyme 1 |
| Reference Data | |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons
Yamashita, Chai, Teramoto et al
EMBO Mol Med (2013) 5 (11), 1710-9 DOI: 10.1002/emmm.201302935
Yamashita, Chai, Teramoto et al
EMBO Mol Med (2013) 5 (11), 1710-9 DOI: 10.1002/emmm.201302935
Cited by 66
AI Summary: OriGene products contributed to this study by providing the anti-TARDBP (TDP-43) antibody (Cat# TA800918) used for immunohistochemical analysis to assess TDP-43 expression in motor neurons.
Co-occurrence of TDP-43 mislocalization with reduced activity of an RNA editing enzyme, ADAR2, in aged mouse motor neurons
Hideyama, Teramoto, Hachiga et al
PLoS One (2012) 7 (8), e43469 DOI: 10.1371/journal.pone.0043469
Hideyama, Teramoto, Hachiga et al
PLoS One (2012) 7 (8), e43469 DOI: 10.1371/journal.pone.0043469
Cited by 28
AI Summary: OriGene products, specifically the mouse Adar2 (NM_019662) qPCR primer pair (catalog #MP210451), were used in this study to quantitatively measure Adar2 mRNA expression levels in mouse spinal cords, contributing to the analysis of age-related changes in ADAR2 expression associated with TDP-43 mislocalization.
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
