MTGR1 (CBFA2T2) Sheep Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | Western Blot: 1 - 10 µg/ml. |
| Reactivity | Human |
| Antibody Host | Sheep |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | C terminal portion of recombinant protein |
| Specificity | This antibody reacts to Myeloid Tumor Related Gene (MTGR1) (AML1-MTG8 binding protein or ETH). |
| Buffer | Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2µm sterile filtered) |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CBFA2/RUNX1 translocation partner 2 |
| Database Link | |
| Background | Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF-dependent proliferation of L-G cells and to interfere with AML1-dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis. |
| Synonyms | EHT, MTGR1, MTG8-like protein, MTG8-related protein 1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Transcription Factors |
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