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Eph receptor B1 (EPHB1) (SAM Region) Sheep Polyclonal Antibody

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SKU
AP05061PU-N
Eph receptor B1 (EPHB1) (SAM Region) sheep polyclonal antibody, Purified
Size:
250 ug
Conjugation:
Unconjugated
  $775.00
5 Days*
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View other "Eph receptor B1 or NP_004432" antibodies

Specifications
Specifications
Product Data
Application IP
Recommended Dilution Western Blot: 1 - 10 µg/ml.
Immunoprecipitation: 10 - 20 µg/ml.
Reactivity Human
Antibody Host Sheep
Isotype IgG
Clonality Polyclonal
Immunogen A GST fusion protein ephB1 (Elk receptor) -SAM corresponding to amino
Specificity This antibody reacts to ephB1 (Elk receptor) - SAM.
Buffer Phosphate buffered saline with 0.08% sodium azide
State: Purified
State: Liquid purified Ig (0.2 µm sterile filtered)
Concentration lot specific
Conjugation Unconjugated
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch
Shipping Blue Ice
Gene Name EPH receptor B1
Database Link
Background The immunogen used for the anti-human ephB1 (Elk receptor) -SAM region was a GST fusion protein ephB1 (Elk receptor) -SAM corresponding to amino acid sequence 883 - 984 of the C terminus region and having a molecular weight of 116 kD. ephB1, previously known as Elk (eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
Synonyms EPHT2, NET, HEK6, ELK, EPH2, Ephrin type-B receptor 1
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Axon guidance
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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