GJA1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | Western Blot: 1/500-1/1000. Incubate membrane with diluted antibody in 5% nonfat milk, 1xTBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. Immunohistochemistry on Paraffin Sections: 1/50-1/100. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic KLH conjugated Peptide sequence around amino acids 365~369 (R-A-S-S-R) from Human Connexin-43. |
| Specificity | This antibody detects endogenous levels of total Connexin 43 protein. |
| Buffer | PBS (without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl State: Aff - Purified State: Liquid purified IgG fraction Stabilizer: 50% Glycerol Preservative: 0.02% Sodium Azide |
| Concentration | lot specific |
| Purification | Affinity Chromatography using epitope-specific immunogen |
| Conjugation | Unconjugated |
| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | gap junction protein alpha 1 |
| Database Link | |
| Background | GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5. |
| Synonyms | Gap junction alpha-1 protein, Connexin-43, GJAL |
| Note | Molecular Weight: 43 kDa |
| Reference Data | |
| Protein Categories | Growth Factors, Membrane Proteins |
Reviews
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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