Encephalopsin (OPN3) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200. |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to amino acids 176-220 of Human Encephalopsin. |
| Specificity | This antibody detects endogenous levels of Encephalopsin protein. (region surrounding Phe202) |
| Buffer | Phosphate Buffered Saline (PBS), pH~ 7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% by SDS-PAGE) Preservative: 15 mM Sodium Azide |
| Concentration | 1.0 mg/ml |
| Purification | Affinity Chromatography using epitope-specific immunogen |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 47.0 kDa |
| Gene Name | opsin 3 |
| Database Link | |
| Background | Opsins, including Encephalopsin, are members of the superfamily of guanine nucleotide-binding protein (G protein)-coupled receptors, which function through the activation of a G protein and an effector enzyme. Opsin proteins consist of a single polypeptide chain of 340 to 500 amino acids that form 7 alpha-helical transmembrane regions connected by cytoplasmic and extracellular loops. |
| Synonyms | Encephalopsin, Panopsin, OPN3, ECPN |
| Reference Data | |
| Protein Categories | GPCR, Membrane Proteins |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Pérez-Cerezales, Boryshpolets, Afanzar et al
Sci Rep (2015) 5, 16146 DOI: 10.1038/srep16146
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