NMBR Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, IF, WB |
|---|---|
| Recommended Dilution | IF:1/50-200 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide, corresponding to amino acids 235-280 of Human NMBR. |
| Specificity | This antibody detects endogenous levels of Neuromedin B receptor / NMBR protein (region surrounding Leu264). |
| Buffer | Phosphate buffered saline (PBS), pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium azide |
| Concentration | 1.0 mg/ml |
| Purification | Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 43 kDa |
| Gene Name | neuromedin B receptor |
| Database Link | |
| Background | The bombesin receptor family includes the gastrin-releasing peptide (GRPR) and neuromedin B (NMBR) receptors. Both receptors are expressed in various brain regions and in the digestive tract. NMBR belongs to the G proteincoupled receptor 1 family. The gene encoding NMBR protein maps to chromosome 6q21-qter. NMBR, an integral membrane protein, binds neuromedin B, a mitogen and growth factor for gastrointestinal epithelial tissue and normal and neoplastic lung. |
| Synonyms | NMB-R, NMBR |
| Reference Data | |
| Protein Categories | GPCR, Growth Factors, Membrane Proteins |
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