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EMR2 (ADGRE2) Rabbit Polyclonal Antibody

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SKU
AP01214PU-N
EMR2 (ADGRE2) rabbit polyclonal antibody, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated
  $495.00
7 Weeks*
Bulk/Customize

View other "ADGRE2 or NP_038475.2" antibodies

Specifications
Specifications
Product Data
Application IF, WB
Recommended Dilution WB:1/500-1000, IF:1/50-200
Reactivity Human
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 130-178 of Human EMR2.
Specificity This antibody detects endogenous levels of EMR2 protein. (region surrounding Leu160)
Buffer Phosphate buffered saline (PBS), pH~7.2
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
Preservative: 0.05% Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen.
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: One year from despatch.
Shipping Blue Ice
Predicted Protein Size ~ 90 kDa
Gene Name adhesion G protein-coupled receptor E2
Database Link
Background EMR2 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system, where it has been shown to be restricted specifically to monocytes and granulocytes. Family members are characterized by an extended extracellular region with a variable number of N terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 3 on chromosome 19. This protein does not interact with the ligand decay accelerating factor for complement, unlike the related CD97 antigen, and indicates that these very closely related proteins likely have nonredundant functions. This gene results in multiple transcripts encoding distinct isoforms. ESTs have been isolated from blood, colon, lymph node, placenta, spleen, testis, and uterus libraries.
Reference Data
Protein Categories CD Markers, GPCR, Growth Factors, Membrane Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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