CD1B Mouse Monoclonal Antibody [Clone ID: RIV12]

CAT#: AM50212PU-T

CD1B mouse monoclonal antibody, clone RIV12, Purified

Product Images

FCM staining of Human PBMCs using CD1b Antibody AM50217PU (Clone RIV12).

Specifications

Product Data

• Clone Name: RIV12
• Applications: FC, IF, IHC, IP
• Recommended Dilution: ELISA: Use BSA free Antibody for coating.
  Flow Cytometry: 0.5-1 μg/million cells.
  Immunofluorescence: 1-2 μg/ml.
  Immunoprecipitation: 1-2 μg/500 μg protein.
  Functional Studies: Use Antibody without BSA and Azide.
  Immunohistochemistry on Frozen Sections: 0.5-1 μg/ml for 30 min at RT.
  Positive Control: MOLT4 cells. Human thymus.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human peripheral lymphocytes.
• Specificity: The Mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta 2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
  Cellular Localization: Cell surface.
• Formulation: 10mM PBS
  State: Purified
  State: Liquid purified IgG fraction from Bioreactor Concentrate
  Stabilizer: 0.05% BSA
  Preservative: 0.05% Sodium Azide
• Concentration: lot specific
• Purification: Protein A/G Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 44 kDa
• Gene Name: CD1b molecule
• Database Link:
  Entrez Gene 910 Human
  UniProt ID P29016
• Synonyms: CD1; CD1A; MGC125990; MGC125991; R1