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CD1b (T-Cell Surface Glycoprotein) Mouse Monoclonal Antibody [Clone ID: RIV12]

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SKU
AM50212PU-T
CD1b (T-Cell Surface Glycoprotein) mouse monoclonal antibody, clone RIV12, Purified
Size:
20 ug 100 ug
Conjugation:
Unconjugated
  $370.00
2 Weeks*
Bulk/Customize

View other "CD1B or NP_001755.1" antibodies

Specifications
Specifications
Product Data
Clone Name RIV12
Application ELISA, FC, IF, IHC, IP
Recommended Dilution ELISA: Use BSA free Antibody for coating.
Flow Cytometry: 0.5-1 μg/million cells.
Immunofluorescence: 1-2 μg/ml.
Immunoprecipitation: 1-2 μg/500 μg protein.
Functional Studies: Use Antibody without BSA and Azide.
Immunohistochemistry on Frozen Sections: 0.5-1 μg/ml for 30 min at RT.
Positive Control: MOLT4 cells. Human thymus.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human peripheral lymphocytes
Specificity Cellular Localization: Cell membrane, Endosome membrane, Lysosome membrane
Buffer 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration lot specific
Purification Protein A/G Chromatography
Conjugation Unconjugated
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 49kDa
Gene Name CD1b molecule
Database Link
Background The Mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
Synonyms A1 domain; CD1B; Cortical thymocyte antigen CD1B; hTa1 thymocyte antigen; Ly38; T6/Leu6; T cell surface glycoprotein CD1b
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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