Park7 Mouse Monoclonal Antibody [Clone ID: 4H4]
Specifications
| Product Data | |
| Clone Name | 4H4 |
|---|---|
| Application | IF, WB |
| Recommended Dilution | Western blotting: 1/2000. Immunofluorescence: 1/500. |
| Reactivity | Bovine, Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length recombinant human park7 expressed in and purified from E. coli. |
| Specificity | This antibody is specific for the ~21k park7 protein. |
| Buffer | PBS State: Purified State: Liquid purified IgG fraction from Culture Supernatant Preservative: 10 mM Sodium Azide |
| Purification | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | Parkinsonism associated deglycase |
| Database Link | |
| Background | Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011). |
| Synonyms | Oncogene DJ1, Parkinson disease protein 7 |
| Reference Data | |
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