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MAGE-1 (Target for Cancer Immunotherapy) Mouse Monoclonal Antibody [Clone ID: MA454]

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SKU
AM32863PU-T
MAGE-1 (Target for Cancer Immunotherapy) mouse monoclonal antibody, clone MA454, Purified
Size:
20 ug 100 ug
Conjugation:
Unconjugated
  $370.00
2 Weeks*
Bulk/Customize

View other "MAGEA1" antibodies

Specifications
Specifications
Product Data
Clone Name MA454
Application FC, IF, IHC, IP, WB
Recommended Dilution ELISA (Use Antibody without BSA For coating).
Flow Cytometry: 0.5-1 µg/106 cells.
Immunofluorescence: 1-2 µg/ml.
Western Blot: 0.5-1 µg/ml.
Immunoprecipitation: 1-2 µg/500 µg protein lysate.
Immunohistochemistry on Frozen and Formallin-Fixed Paraffin Sections: 0.5-1 µg/ml for 30 minutes at RT.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Positive Control: Melanoma cell lines. Melanomas, gliomas, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, and renal cell carcinomas.
Reactivity Canine, Dog, Human, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant full-length human MAGE-A1 protein
Specificity Cellular Localization: Cytoplasm, Nucleus
Buffer 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration lot specific
Purification Protein A/G Chromatography
Conjugation Unconjugated
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 42-46kDa
Gene Name MAGE family member A1
Database Link
Background Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
Synonyms MZ2 E, cancer/testis antigen 1.1, CT1.1, MAGE1A, MAGEA1, Melanoma antigen family A 1, Melanoma associated antigen 1, Melanoma associated antigen MZ2 E
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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