Cd8a Mouse Monoclonal Antibody [Clone ID: ANK44]
$905.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | ANK44 |
|---|---|
| Application | FC, IHC, IP |
| Recommended Dilution | Flow Cytometry. Immunoprecipitation. Immunohistochemical on Frozen Sections. |
| Reactivity | Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | The ANK44 monoclonal antibody was generated by immunizing mice with IL-2-activated cultured NK cells of Wag rats (Giezeman-Smits et al., 1998). |
| Specificity | The antigen recognized by this Monoclonal antibody ANK44 is highly expressed on Rat NK cells after IL-2-activation. The antigen is not expressed by unstimulated NK cells. ANK44 also binds to Rat gamma/delta-TCR T cells. It does not bind to alpha/beta-TCR T cells or to B cells. The ANK44 Monoclonal antibody is Rat strain-independent. |
| Buffer | State: Supernatant State: Hybridoma Culture Supernatant Preservative: 0.05% Sodium Azide |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for Two months or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD8a molecule |
| Database Link | |
| Background | Natural Killer Cells (NK) are large, granular, bone-marrow derived lymphocytes and are a component of innate immune defense. They are activated in response to interferons or macrophage-derived cytokines. Rather than destroying the attacking microorganisms directly, NK cells attack cells that have been infected by the microbes. NK cells contain special proteins in their cytoplasm, such as proteases called granzymes as well as Perforin. Perforin makes pores in the target cell membrane, allowing the granzymes, water and ions to diffuse into the cell. This causes expansion of the cell until it eventually lyses under pressure. Individuals who lack NK cells are highly susceptible to early phases of herpes virus infection. |
| Synonyms | CD8 alpha chain, CD8A, MAL |
| Reference Data | |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
