Vinculin (VCL) Mouse Monoclonal Antibody [Clone ID: FB11]
$1,085.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | FB11 |
|---|---|
| Application | ELISA, IHC, WB |
| Recommended Dilution | Western blotting: Use at least 1/1000. Immunohistochemistry on Frozen Sections. Immunoassays for cellular and tumor biology. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified Vinculin from Human smooth muscle. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. |
| Specificity | The antibody reacts with the Vinculin antigen. In Immunoblotting the antibody identifies a 130 kD polypeptide. |
| Buffer | PBS State: Purified State: Liquid purified Ig fraction Stabilizer: 1% BSA Preservative: 0.09% Sodium Azdie |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | vinculin |
| Database Link | |
| Background | Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin. Vinculin binds to actin capping protein and alpha actinin, which in turn binds to actin. The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin. Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix. |
| Synonyms | Metavinculin |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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